The Longevity Vault

The Longevity Vault

The Only Supplement I’ve Taken for 20 Years

It activates the same pathways as fasting (& protects joints):

Kat Fu, M.S., M.S.'s avatar
Kat Fu, M.S., M.S.
Dec 06, 2025
∙ Paid

I’ve always kept my supplement shelf small.

Most rotate in and out as new evidence emerges or priorities change. One, however, has stayed for ~20 years.

(by the way, if you haven’t seen it, my article If I Could Only Take 1 Supplement for the Rest of My Life looks at a different choice for a different reason.)

And, I first added it for joint protection, 20 years ago!

Why?

While muscles often take the spotlight in conversations about physical aging, healthy joints are the prerequisite for building & maintaining muscle. They are the foundation for training, moving freely & sustaining independence in daily life.

This compound supports the tissue that makes those movements possible.

What’s more, research shows this same compound activates longevity pathways— the same processes triggered by fasting.

It isn’t vitamin D, magnesium, creatine, omega-3, or CoQ10. And it isn’t what most expect to find in a longevity protocol.

Here is the supplement I have kept for ~20 years — one that not only protects joints but also activates longevity pathways:

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